Keep in mind Owls initial example at the beginning of the essay on erythromycin A which was well known and well characterized. It took Lilly 9 years to synthesize artificially. Yes, organic synthesis methods have advanced since then, but figuring out how to actually make a "de-vovo" molecule takes years of trial and error on the bench of…
Keep in mind Owls initial example at the beginning of the essay on erythromycin A which was well known and well characterized. It took Lilly 9 years to synthesize artificially. Yes, organic synthesis methods have advanced since then, but figuring out how to actually make a "de-vovo" molecule takes years of trial and error on the bench of a organic chemistry lab, even for a stellar organic chemist. Latter consider them fortunate if only one of their molecules actually make it into the real world during their lifetime.
There is no start-up who can afford to wait for years to synthesize the list of in principal synthesizable small molecules, nor afford it (the equipment and infrastructure necessary is not cheap).
Keep in mind Owls initial example at the beginning of the essay on erythromycin A which was well known and well characterized. It took Lilly 9 years to synthesize artificially. Yes, organic synthesis methods have advanced since then, but figuring out how to actually make a "de-vovo" molecule takes years of trial and error on the bench of a organic chemistry lab, even for a stellar organic chemist. Latter consider them fortunate if only one of their molecules actually make it into the real world during their lifetime.
There is no start-up who can afford to wait for years to synthesize the list of in principal synthesizable small molecules, nor afford it (the equipment and infrastructure necessary is not cheap).